Gene name:

Fgf9(Fgf-9);

Protein name:

Glia-activating factor(GAF);

Alternative:

Fibroblast growth factor 9(FGF-9);HBGF-9;

Organism:

Rat (Rattus norvegicus). 

Sub Unit:

Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.

Function:

Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.

Subcellular Location:

Secreted

Sequence length:

208

Sequence:

50:

MAPLGEVGSY | FGVQDAVPFG | NVPVLPVDSP | VLLSDHLGQS | EAGGLPRGPA | 

100:

VTDLDHLKGI | LRRRQLYCRT | GFHLEIFPNG | TIQGTRKDHS | RFGILEFISI | 

150:

AVGLVSIRGV | DSGLYLGMNE | KGELYGSEKL | TQECVFREQF | EENWYNTYSS | 

200:

NLYKHVDTGR | RYYVALNKDG | TPREGTRTKR | HQKFTHFLPR | PVDPDKVPEL | 

208:

YKDILSQS

3D Structure:

N/A

Predicted Eptitope:

Related Databases

Uniprot:

P36364